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Dosage Compensation in Mammals
Many organisms show major chromosomal differences between sexes. In mammals, females have two copies of a large, gene-rich chromosome, the X, whereas males have one X and a small, gene-poor Y. The imbalance in expression of several hundred genes is lethal if not dealt with by dosage compensation. Th...
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| Udgivet i: | Cold Spring Harb Perspect Biol |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4355265/ https://ncbi.nlm.nih.gov/pubmed/25731764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a019406 |
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