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PRL-3 mediates the protein maturation of ULBP2 by regulating the tyrosine phosphorylation of HSP60
Many malignant cells release the NKG2D ligand ULBP2 from their cell surface to evade immunosurveillance by natural killer cells and CD8 T cells. Although the shedding mechanism remains unclear, various inhibitors of matrix metalloproteinases have been shown to efficiently block the release of solubl...
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| Publicado en: | J Immunol |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4355089/ https://ncbi.nlm.nih.gov/pubmed/25687758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400817 |
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