Hypotonic Activation of the Myo-Inositol Transporter SLC5A3 in HEK293 Cells Probed by Cell Volumetry, Confocal and Super-Resolution Microscopy

Swelling-activated pathways for myo-inositol, one of the most abundant organic osmolytes in mammalian cells, have not yet been identified. The present study explores the SLC5A3 protein as a possible transporter of myo-inositol in hyponically swollen HEK293 cells. To address this issue, we examined t...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Andronic, Joseph, Shirakashi, Ryo, Pickel, Simone U., Westerling, Katherine M., Klein, Teresa, Holm, Thorge, Sauer, Markus, Sukhorukov, Vladimir L.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355067/
https://ncbi.nlm.nih.gov/pubmed/25756525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119990
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