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A mouse model of urofacial syndrome with dysfunctional urination

Urofacial syndrome (UFS) is an autosomal recessive disease with severe dysfunctional urination including urinary incontinence (UI). Biallelic mutations of HPSE2 are discovered from UFS patients, suggesting that HPSE2 is a candidate disease gene. Here, we show that deletion of Hpse2 is sufficient to...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Guo, Chunming, Kaneko, Satoshi, Sun, Ye, Huang, Yichen, Vlodavsky, Israel, Li, Xiaokun, Li, Zhong-Rong, Li, Xue
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355027/
https://ncbi.nlm.nih.gov/pubmed/25510506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu613
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