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A mouse model of urofacial syndrome with dysfunctional urination

Urofacial syndrome (UFS) is an autosomal recessive disease with severe dysfunctional urination including urinary incontinence (UI). Biallelic mutations of HPSE2 are discovered from UFS patients, suggesting that HPSE2 is a candidate disease gene. Here, we show that deletion of Hpse2 is sufficient to...

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Publicat a:Hum Mol Genet
Autors principals: Guo, Chunming, Kaneko, Satoshi, Sun, Ye, Huang, Yichen, Vlodavsky, Israel, Li, Xiaokun, Li, Zhong-Rong, Li, Xue
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355027/
https://ncbi.nlm.nih.gov/pubmed/25510506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu613
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