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A novel, efficient, randomized selection trial comparing combinations of drug therapy for ALS

Combining agents with different mechanisms of action may be necessary for meaningful results in treating ALS. The combinations of minocycline-creatine and celecoxib-creatine have additive effects in the murine model. New trial designs are needed to efficiently screen the growing number of potential...

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Detalhes bibliográficos
Publicado no:Amyotroph Lateral Scler
Main Authors: GORDON, PAUL H., CHEUNG, YING-KUEN, LEVIN, BRUCE, ANDREWS, HOWARD, DOORISH, CAROLYN, MACARTHUR, ROBERT B., MONTES, JACQUELINE, BEDNARZ, KATE, FLORENCE, JULAINE, ROWIN, JULIE, BOYLAN, KEVIN, MOZAFFAR, TAHSEEN, TANDAN, RUP, MITSUMOTO, HIROSHI, KELVIN, ELIZABETH A., CHAPIN, JOHN, BEDLACK, RICHARD, RIVNER, MICHAEL, MCCLUSKEY, LEO F., PESTRONK, ALAN, GRAVES, MICHAEL, SORENSON, ERIC J., BAROHN, RICHARD J., BELSH, JERRY M., LOU, JAU-SHIN, LEVINE, TODD, SAPERSTEIN, DAVID, MILLER, ROBERT G., SCELSA, STEPHEN N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354803/
https://ncbi.nlm.nih.gov/pubmed/18608093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17482960802195632
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