Inhibition of Major Drug Metabolizing CYPs by Common Herbal Medicines used by HIV/AIDS Patients in Africa– Implications for Herb-Drug Interactions

The purpose of this study was to evaluate the potential risk of common herbal medicines used by HIV-infected patients in Africa for herb-drug interactions (HDI). High throughput screening assays consisting of recombinant Cytochrome P450 enzymes (CYPs) and fluorescent probes, and parallel artificial...

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Bibliographic Details
Published in:Drug Metab Lett
Main Authors: Awortwe, Charles, Bouic, Patrick J., Masimirembwa, Collen M., Rosenkranz, Bernd
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354708/
https://ncbi.nlm.nih.gov/pubmed/24475926
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