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Avoiding Misannotation of In-Source Fragmentation Products as Cellular Metabolites in Liquid Chromatography–Mass Spectrometry-Based Metabolomics

Liquid chromatography–mass spectrometry (LC-MS) technology allows for rapid quantitation of cellular metabolites, with metabolites identified by mass spectrometry and chromatographic retention time. Recently, with the development of rapid scanning high-resolution high accuracy mass spectrometers and...

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Bibliographic Details
Published in:Anal Chem
Main Authors: Xu, Yi-Fan, Lu, Wenyun, Rabinowitz, Joshua D.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354698/
https://ncbi.nlm.nih.gov/pubmed/25591916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac504118y
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