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Transposon Mediated Integration of Plasmid DNA into the Subventricular Zone of Neonatal Mice to Generate Novel Models of Glioblastoma

An urgent need exists to test the contribution of new genes to the pathogenesis and progression of human glioblastomas (GBM), the most common primary brain tumor in adults with dismal prognosis. New potential therapies are rapidly emerging from the bench and require systematic testing in experimenta...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Calinescu, Anda-Alexandra, Núñez, Felipe Javier, Koschmann, Carl, Kolb, Bradley L., Lowenstein, Pedro R., Castro, Maria G.
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354658/
https://ncbi.nlm.nih.gov/pubmed/25741859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52443
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