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Reconstitution of a Transmembrane Protein, the Voltage-gated Ion Channel, KvAP, into Giant Unilamellar Vesicles for Microscopy and Patch Clamp Studies

Giant Unilamellar Vesicles (GUVs) are a popular biomimetic system for studying membrane associated phenomena. However, commonly used protocols to grow GUVs must be modified in order to form GUVs containing functional transmembrane proteins. This article describes two dehydration-rehydration methods...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Garten, Matthias, Aimon, Sophie, Bassereau, Patricia, Toombes, Gilman E. S.
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354550/
https://ncbi.nlm.nih.gov/pubmed/25650630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52281
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