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Matrix metalloproteinases in atherosclerosis: role of nitric oxide, hydrogen sulfide, homocysteine, and polymorphisms

Atherosclerosis is an inflammatory process that involves activation of matrix metalloproteinases (MMPs); MMPs degrade collagen and allow for smooth-muscle cell migration within a vessel. Moreover, this begets an accumulation of other cellular material, resulting in occlusion of the vessel and ischem...

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Detalhes bibliográficos
Publicado no:Vasc Health Risk Manag
Main Authors: Vacek, Thomas P, Rehman, Shahnaz, Neamtu, Diana, Yu, Shipeng, Givimani, Srikanth, Tyagi, Suresh C
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354431/
https://ncbi.nlm.nih.gov/pubmed/25767394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/VHRM.S68415
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