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Effect of a single nucleotide polymorphism in miR-146a on COX-2 protein expression and lung function in smokers with chronic obstructive pulmonary disease
OBJECTIVE: To evaluate the effect of a single nucleotide polymorphism (rs2910164) in the miR-146a precursor on the expression level of miR-146a, cyclooxygenase-2 (COX2), and production of prostaglandin E2 (PGE2) in lung tissue harvested from smokers with chronic obstructive pulmonary disease, as wel...
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Publicado no: | Int J Chron Obstruct Pulmon Dis |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Dove Medical Press
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4354402/ https://ncbi.nlm.nih.gov/pubmed/25767384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S74345 |
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