Amoxicillin concentrations in relation to beta-lactamase activity in sputum during exacerbations of chronic obstructive pulmonary disease

BACKGROUND: Acute exacerbations of chronic obstructive pulmonary disease (COPD) are often treated with antibiotics. Theoretically, to be maximally effective, the antibiotic concentration at sites of infection should exceed the minimum inhibitory concentration at which 90% of the growth of potential...

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Detalhes bibliográficos
Publicado no:Int J Chron Obstruct Pulmon Dis
Main Authors: Brusse-Keizer, Marjolein, VanderValk, Paul, van der Zanden, Rogier W, Nijdam, Lars, van der Palen, Job, Hendrix, Ron, Movig, Kris
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354398/
https://ncbi.nlm.nih.gov/pubmed/25767383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S70355
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