Transcriptional Response of Polycomb Group Genes to Status Epilepticus in Mice is Modified by Prior Exposure to Epileptic Preconditioning

Exposure of the brain to brief, non-harmful seizures can activate protective mechanisms that temporarily generate a damage-refractory state. This process, termed epileptic tolerance, is associated with large-scale down-regulation of gene expression. Polycomb group (PcG) proteins are master controlle...

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Pubblicato in:Front Neurol
Autori principali: Reynolds, James P., Miller-Delaney, Suzanne F. C., Jimenez-Mateos, Eva M., Sano, Takanori, McKiernan, Ross C., Simon, Roger P., Henshall, David C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2015
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354380/
https://ncbi.nlm.nih.gov/pubmed/25806020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2015.00046
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