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Insulin resistance and white adipose tissue inflammation are uncoupled in energetically challenged Fsp27-deficient mice
Fsp27 is a lipid droplet-associated protein almost exclusively expressed in adipocytes where it facilitates unilocular lipid droplet formation. In mice, Fsp27 deficiency is associated with increased basal lipolysis, ‘browning’ of white fat and a healthy metabolic profile, whereas a patient with cong...
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| 出版年: | Nat Commun |
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| 主要な著者: | , , , , , , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Pub. Group
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4354252/ https://ncbi.nlm.nih.gov/pubmed/25565658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6949 |
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