Multi-omics analysis defines core genomic alterations in pheochromocytomas and paragangliomas

Pheochromocytomas and paragangliomas (PCCs/PGLs) are neural crest-derived tumours with a very strong genetic component. Here we report the first integrated genomic examination of a large collection of PCC/PGL. SNP array analysis reveals distinct copy-number patterns associated with genetic backgroun...

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Udgivet i:Nat Commun
Main Authors: Castro-Vega, Luis Jaime, Letouzé, Eric, Burnichon, Nelly, Buffet, Alexandre, Disderot, Pierre-Hélie, Khalifa, Emmanuel, Loriot, Céline, Elarouci, Nabila, Morin, Aurélie, Menara, Mélanie, Lepoutre-Lussey, Charlotte, Badoual, Cécile, Sibony, Mathilde, Dousset, Bertrand, Libé, Rossella, Zinzindohoue, Franck, Plouin, Pierre François, Bertherat, Jérôme, Amar, Laurence, de Reyniès, Aurélien, Favier, Judith, Gimenez-Roqueplo, Anne-Paule
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354166/
https://ncbi.nlm.nih.gov/pubmed/25625332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7044
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