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Assessment of low-dose cisplatin as a model of nausea and emesis in beagle dogs, potential for repeated administration
Cisplatin is a highly emetogenic cancer chemotherapy agent, which is often used to induce nausea and emesis in animal models. The cytotoxic properties of cisplatin also cause adverse events that negatively impact on animal welfare preventing repeated administration of cisplatin. In this study, we as...
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Publicado no: | Exp Brain Res |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Springer Berlin Heidelberg
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4353862/ https://ncbi.nlm.nih.gov/pubmed/24792501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00221-014-3961-6 |
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