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Assessment of low-dose cisplatin as a model of nausea and emesis in beagle dogs, potential for repeated administration

Cisplatin is a highly emetogenic cancer chemotherapy agent, which is often used to induce nausea and emesis in animal models. The cytotoxic properties of cisplatin also cause adverse events that negatively impact on animal welfare preventing repeated administration of cisplatin. In this study, we as...

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Detalhes bibliográficos
Publicado no:Exp Brain Res
Main Authors: Kenward, Hannah, Pelligand, Ludovic, Elliott, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4353862/
https://ncbi.nlm.nih.gov/pubmed/24792501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00221-014-3961-6
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