A Micropolymorphism Altering the Residue Triad 97/114/156 Determines the Relative Levels of Tapasin Independence and Distinct Peptide Profiles for HLA-A(*)24 Allotypes

While many HLA class I molecules interact directly with the peptide loading complex (PLC) for conventional loading of peptides certain class I molecules are able to present peptides in a way that circumvents the PLC components. We investigated micropolymorphisms at position 156 of HLA-A(*)24 allotyp...

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Détails bibliographiques
Publié dans:J Immunol Res
Auteurs principaux: Badrinath, Soumya, Kunze-Schumacher, Heike, Blasczyk, Rainer, Huyton, Trevor, Bade-Doeding, Christina
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4353853/
https://ncbi.nlm.nih.gov/pubmed/25802875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/298145
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