IP(3) signalling regulates exogenous RNAi in Caenorhabditis elegans

RNA interference (RNAi) is a widespread and widely exploited phenomenon. Here, we show that changing inositol 1,4,5-trisphosphate (IP(3)) signalling alters RNAi sensitivity in Caenorhabditis elegans. Reducing IP(3) signalling enhances sensitivity to RNAi in a broad range of genes and tissues. Conver...

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Dades bibliogràfiques
Publicat a:EMBO Rep
Autors principals: Nagy, Anikó I, Vázquez-Manrique, Rafael P, Lopez, Marie, Christov, Christo P, Sequedo, María Dolores, Herzog, Mareike, Herlihy, Anna E, Bodak, Maxime, Gatsi, Roxani, Baylis, Howard A
Format: Artigo
Idioma:Inglês
Publicat: BlackWell Publishing Ltd 2015
Matèries:
Scientific Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4353841/
https://ncbi.nlm.nih.gov/pubmed/25608529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201439585
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