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Treatment of heterotopic ossification through remote ATP hydrolysis

Heterotopic ossification (HO) is the pathologic development of ectopic bone in soft tissues because of a local or systemic inflammatory insult, such as burn injury or trauma. In HO, mesenchymal stem cells (MSCs) are inappropriately activated to undergo osteogenic differentiation. Through the correla...

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Bibliographic Details
Published in:Sci Transl Med
Main Authors: Peterson, Jonathan R., De La Rosa, Sara, Eboda, Oluwatobi, Cilwa, Katherine E., Agarwal, Shailesh, Buchman, Steven R., Cederna, Paul S., Xi, Chuanwu, Morris, Michael D., Herndon, David N., Xiao, Wenzhong, Tompkins, Ronald G., Krebsbach, Paul H., Wang, Stewart C., Levi, Benjamin
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4353731/
https://ncbi.nlm.nih.gov/pubmed/25253675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3008810
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