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Mutational processes of simple-sequence repeat loci in human populations.

Mutational processes of simple sequence repeats (SSRs) in complex genomes are poorly understood. We examined these processes by introducing a two-phase mutation model. In this model, most mutations are single-step changes, but infrequent large jumps in repeat number also occur. We used computer simu...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Principais autores: Di Rienzo, A, Peterson, A C, Garza, J C, Valdes, A M, Slatkin, M, Freimer, N B
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1994
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43536/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8159720/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.8.3166
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