Deficiency of the Sialyltransferase St3Gal4 Reduces Ccl5-Mediated Myeloid Cell Recruitment and Arrest

RATIONALE: Sialylation by α2,3-sialyltransferases has been shown to be a crucial glycosylation step in the generation of functional selectin ligands. Recent evidence suggests that sialylation also affects the binding of chemokines to their corresponding receptor. OBJECTIVE: Because the chemokine rec...

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Veröffentlicht in:Circ Res
Hauptverfasser: Döring, Yvonne, Noels, Heidi, Mandl, Manuela, Kramp, Birgit, Neideck, Carlos, Lievens, Dirk, Drechsler, Maik, Megens, Remco T.A., Tilstam, Pathricia V., Langer, Marcella, Hartwig, Helene, Theelen, Wendy, Marth, Jamey D., Sperandio, Markus, Soehnlein, Oliver, Weber, Christian
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4353583/
https://ncbi.nlm.nih.gov/pubmed/24425712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.114.302426
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