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Using RNA-interference to Investigate the Innate Immune Response in Mouse Macrophages

Macrophages are key phagocytic innate immune cells. When macrophages encounter a pathogen, they produce antimicrobial proteins and compounds to kill the pathogen, produce various cytokines and chemokines to recruit and stimulate other immune cells, and present antigens to stimulate the adaptive immu...

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Bibliographic Details
Published in:J Vis Exp
Main Authors: De Arras, Lesly, Guthrie, Brandon S., Alper, Scott
Format: Artigo
Language:Inglês
Published: MyJove Corporation 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4353398/
https://ncbi.nlm.nih.gov/pubmed/25407484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/51306
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