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Generation and Purification of Human INO80 Chromatin Remodeling Complexes and Subcomplexes

INO80 chromatin remodeling complexes regulate nucleosome dynamics and DNA accessibility by catalyzing ATP-dependent nucleosome remodeling. Human INO80 complexes consist of 14 protein subunits including Ino80, a SNF2-like ATPase, which serves both as the catalytic subunit and the scaffold for assembl...

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Bibliografiske detaljer
Udgivet i:J Vis Exp
Main Authors: Chen, Lu, Ooi, Soon-Keat, Conaway, Ronald C., Conaway, Joan W.
Format: Artigo
Sprog:Inglês
Udgivet: MyJove Corporation 2014
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4353394/
https://ncbi.nlm.nih.gov/pubmed/25407439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/51720
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