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Carotid Artery Infusions for Pharmacokinetic and Pharmacodynamic Analysis of Taxanes in Mice

When proposing the use of a drug, drug combination, or drug delivery into a novel system, one must assess the pharmacokinetics of the drug in the study model. As the use of mouse models are often a vital step in preclinical drug discovery and drug development(1-8), it is necessary to design a system...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Jacobs, Joely D., Hopper-Borge, Elizabeth A.
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4353391/
https://ncbi.nlm.nih.gov/pubmed/25407935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/51917
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