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Enzyme transformation to modulate the ligand-receptor interactions between small molecules

Enzymatic transformation is a fundamental process to control ligand-receptor interactions among proteins for signal transduction in cells. Here we report the first example of enzymatic transformation regulated ligand-receptor interactions of small molecules, in which enzymatic reaction changes the s...

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Bibliographic Details
Published in:Chem Commun (Camb)
Main Authors: Shi, Junfeng, Du, Xuewen, Yuan, Dan, Haburcak, Richard, Wu, Dongdong, Zhou, Ning, Xu, Bing
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352935/
https://ncbi.nlm.nih.gov/pubmed/25703347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4cc10374b
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