DNA methylation at hepatitis B viral integrants is associated with methylation at flanking human genomic sequences

Integration of DNA viruses into the human genome plays an important role in various types of tumors, including hepatitis B virus (HBV)–related hepatocellular carcinoma. However, the molecular details and clinical impact of HBV integration on either human or HBV epigenomes are unknown. Here, we show...

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Vydáno v:Genome Res
Hlavní autoři: Watanabe, Yoshiyuki, Yamamoto, Hiroyuki, Oikawa, Ritsuko, Toyota, Minoru, Yamamoto, Masakazu, Kokudo, Norihiro, Tanaka, Shinji, Arii, Shigeki, Yotsuyanagi, Hiroshi, Koike, Kazuhiko, Itoh, Fumio
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2015
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352876/
https://ncbi.nlm.nih.gov/pubmed/25653310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.175240.114
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