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Integrity of the yeast mitochondrial genome, but not its distribution and inheritance, relies on mitochondrial fission and fusion

Mitochondrial DNA (mtDNA) is essential for mitochondrial and cellular function. In Saccharomyces cerevisiae, mtDNA is organized in nucleoprotein structures termed nucleoids, which are distributed throughout the mitochondrial network and are faithfully inherited during the cell cycle. How the cell di...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Osman, Christof, Noriega, Thomas R., Okreglak, Voytek, Fung, Jennifer C., Walter, Peter
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352819/
https://ncbi.nlm.nih.gov/pubmed/25730886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1501737112
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