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Isolation of the human peroxisomal acyl-CoA oxidase gene: organization, promoter analysis, and chromosomal localization.

Peroxisomal acyl-CoA oxidase (ACOX; EC 1.3.3.6) is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs, and it donates electrons directly to molecular oxygen, thereby producing H2O2. The discovery of carcinogenic peroxisome p...

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Detalles Bibliográficos
Main Authors: Varanasi, U, Chu, R, Chu, S, Espinosa, R, LeBeau, M M, Reddy, J K
Formato: Artigo
Idioma:Inglês
Publicado: 1994
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC43524/
https://ncbi.nlm.nih.gov/pubmed/8159712
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