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Molecular prenatal diagnosis of megalencephalic leukoencephalopathy with subcortical cysts in a child from southwest of Iran

Megalencephalic leukoencephalopathy (MLC) is a rare neurological disorder with an autosomal recessive pattern. Clinical diagnosis was based on macrocephaly, recurrent seizure, and magnetic resonance imaging (MRI). Here we report first finding of a novel homozygous single base deletion in the MLC1 ge...

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Detalhes bibliográficos
Publicado no:Clin Case Rep
Main Authors: Shariati, Gholamreza, Hamid, Mohammad, Saberi, Alihossein, Andashti, Behnaz, Galehdari, Hamid
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352366/
https://ncbi.nlm.nih.gov/pubmed/25767710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ccr3.168
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