Induced pluripotent stem cells have similar immunogenic and more potent immunomodulatory properties compared with bone marrow-derived stromal cells in vitro

AIM: To evaluate the in vitro immunogenic and immunomodulatory properties of induced pluripotent stem cells (iPSCs) compared with bone marrow-derived mesenchymal stromal cells (MSCs). MATERIALS & METHODS: Mouse embryonic fibroblasts (MEFs) were isolated from C3HeB/FeJ and C57BL/6J mice, and repr...

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Veröffentlicht in:Regen Med
Hauptverfasser: Schnabel, Lauren V, Abratte, Christian M, Schimenti, John C, Felippe, M Julia Bevilaqua, Cassano, Jennifer M, Southard, Teresa L, Cross, Jessica A, Fortier, Lisa A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352342/
https://ncbi.nlm.nih.gov/pubmed/24773530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/rme.14.29
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