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Common synonymous variants in ABCA4 are protective for chloroquine induced maculopathy (toxic maculopathy)
BACKGROUND: Chloroquine (CQ) and hydroxychloroquine (HCQ) are used to treat auto-immune related diseases such as rheumatoid arthritis (RA) or systemic lupus erythematosus. Both drugs however can cause retinal toxicity eventually leading to irreversible maculopathy and retinopathy. Established risk f...
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| Publicado no: | BMC Ophthalmol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4352241/ https://ncbi.nlm.nih.gov/pubmed/25884411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12886-015-0008-0 |
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