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Cyclodextrine Screening for the Chiral Separation of Amlodipine Enantiomers by Capillary Electrophoresis

Purpose: Amlodipine is a long acting, dihydropyridine type calcium channel blocker frequently used in the treatment of hypertension and coronary insufficiency. The calcium channel blocking activity resides primarily in the S-amlodipine enantiomer, while R-amlodipine is a potent inhibitor of smooth m...

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Publicado en:Adv Pharm Bull
Autores principales: Hancu, Gabriel, Budău, Monica, Kántor, Lajos Kristóf, Cârje, Anca
Formato: Artigo
Lenguaje:Inglês
Publicado: Tabriz University of Medical Sciences 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352221/
https://ncbi.nlm.nih.gov/pubmed/25789217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5681/apb.2015.005
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