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Chronic Inhibition of Hypothalamic-Pituitary-Ovarian Axis and Body Weight Gain by Brain-Directed Delivery of EstradioI-17β in Female Rats

The effect of preferential delivery of estradiol (E(2)) into the brain on both the hypothalamic-pituitary-ovarian axis and weight gain was studied in female rats. When E(2) was coupled to a lipoidal dihydropyridine-pyridinium carrier, the resulting carrier E(2) complex (CE), upon a single intravenou...

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Detalhes bibliográficos
Publicado no:Neuroendocrinology
Main Authors: Sarkar, Dipak K., Friedman, Susan J., Yen, Samuel S.C., Frautschy, Sally A.
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352090/
https://ncbi.nlm.nih.gov/pubmed/2674763
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