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Improved Development of Somatic Cell Cloned Mouse Embryos by Vitamin C and Latrunculin A

Impaired development of embryos produced by somatic cell nuclear transfer (SCNT) is mostly associated with faulty reprogramming of the somatic nucleus to a totipotent state and can be improved by treatment with epigenetic modifiers. Here we report that addition of 100 μM vitamin C (VitC) to embryo c...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Mallol, Anna, Santaló, Josep, Ibáñez, Elena
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352067/
https://ncbi.nlm.nih.gov/pubmed/25749170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120033
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