Preclinical Studies Identify Non-Apoptotic Low-Level Caspase-3 as Therapeutic Target in Pemphigus Vulgaris

The majority of pemphigus vulgaris (PV) patients suffer from a live-threatening loss of intercellular adhesion between keratinocytes (acantholysis). The disease is caused by auto-antibodies that bind to desmosomal cadherins desmoglein (Dsg) 3 or Dsg3 and Dsg1 in mucous membranes and skin. A currentl...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Luyet, Camille, Schulze, Katja, Sayar, Beyza S., Howald, Denise, Müller, Eliane J., Galichet, Arnaud
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2015
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352034/
https://ncbi.nlm.nih.gov/pubmed/25748204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119809
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