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miR-17 deregulates a core RUNX1-miRNA mechanism of CBF acute myeloid leukemia
BACKGROUND: Core Binding Factor acute myeloid leukemia (CBF-AML) with t(8;21) RUNX1-MTG8 or inv(16) CBFB-MYH11 fusion proteins often show upregulation of wild type or mutated KIT receptor. However, also non-CBF-AML frequently displays upregulated KIT expression. In the first part of this study we sh...
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| Publicado no: | Mol Cancer |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4351976/ https://ncbi.nlm.nih.gov/pubmed/25612891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-014-0283-z |
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