PRMT9 is a Type II methyltransferase that methylates the splicing factor SAP145

The human genome encodes a family of nine protein arginine methyltransferases (PRMT1-9), which members can catalyze three distinct types of methylation on arginine residues. Here, we identify two spliceosome-associated proteins – SAP145 and SAP49 – as PRMT9 binding partners, linking PRMT9 to U2snRNP...

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Vydáno v:Nat Commun
Hlavní autoři: Yang, Yanzhong, Hadjikyriacou, Andrea, Xia, Zheng, Gayatri, Sitaram, Kim, Daehoon, Zurita-Lopez, Cecilia, Kelly, Ryan, Guo, Ailan, Li, Wei, Clarke, Steven G., Bedford, Mark T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351962/
https://ncbi.nlm.nih.gov/pubmed/25737013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7428
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