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Association of rare variation in the glutamate receptor gene SLC1A2 with susceptibility to bipolar disorder and schizophrenia

The SLC1A2 gene encodes the excitatory amino acid transporter 2 (EAAT2). Glutamate is the major mediator of excitatory neurotransmission and EAAT2 is responsible for clearing the neurotransmitter from the synaptic cleft. Genetic variation in SLC1A2 has been implicated in a range of neurological and...

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Détails bibliographiques
Publié dans:Eur J Hum Genet
Auteurs principaux: Fiorentino, Alessia, Sharp, Sally I, McQuillin, Andrew
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351899/
https://ncbi.nlm.nih.gov/pubmed/25406999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2014.261
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