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The alternative splicing regulator Tra2b is required for somitogenesis and regulates splicing of an inhibitory Wnt11b isoform

Alternative splicing is pervasive in vertebrates, yet little is known about most isoforms or their regulation. transformer-2b (tra2b) encodes a splicing regulator whose endogenous function is poorly understood. Tra2b knockdown in Xenopus results in embryos with multiple defects, including defective...

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Bibliografische gegevens
Gepubliceerd in:Cell Rep
Hoofdauteurs: Dichmann, Darwin S, Walentek, Peter, Harland, Richard M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351874/
https://ncbi.nlm.nih.gov/pubmed/25620705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.12.046
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