Cilengitide in Patients with Recurrent Glioblastoma: The Results of NABTC 03-02, a Phase II Trial with Measures of Treatment Delivery

PURPOSE: Cilengitide is a cyclic pentapeptide that is a specific inhibitor of the αvβ3 and αvβ5 integrins. Preclinical studies demonstrate antiangiogenic activity and anti-invasive activity in a number of glioma models. This study was designed to evaluate the efficacy and tumor delivery of cilengiti...

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Vydáno v:J Neurooncol
Hlavní autoři: Gilbert, Mark R., Kuhn, John, Lamborn, Kathleen R., Lieberman, Frank, Wen, Patrick Y., Mehta, Minesh, Cloughesy, Timothy, Lassman, Andrew B., DeAngelis, Lisa M., Chang, Susan, Prados, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351869/
https://ncbi.nlm.nih.gov/pubmed/21739168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-011-0650-1
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