The Effect of Malnutrition on the Pharmacokinetics and Virologic Outcomes of Lopinavir, Efavirenz and Nevirapine in Food Insecure HIV-Infected Children in Tororo, Uganda

BACKGROUND: Malnutrition may impact the pharmacokinetics (PK) of antiretroviral medications and virologic responses in HIV-infected children. We therefore evaluated the PK of nevirapine (NVP), efavirenz (EFV) and lopinavir (LPV) in associations with nutritional status in a cohort of HIV-infected Uga...

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Publicado no:Pediatr Infect Dis J
Main Authors: Bartelink, Imke H., Savic, Rada M., Dorsey, Grant, Ruel, Theodore, Gingrich, David, Scherpbier, Henriette J., Capparelli, Edmund, Jullien, Vincent, Young, Sera L., Achan, Jane, Plenty, Albert, Charlebois, Edwin, Kamya, Moses, Havlir, Diane, Aweeka, Francesca
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351793/
https://ncbi.nlm.nih.gov/pubmed/25742090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/INF.0000000000000603
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