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Transport domain unlocking sets the uptake rate of an aspartate transporter
Glutamate transporters terminate neurotransmission by clearing synaptically released glutamate from the extracellular space, allowing repeated rounds of signaling and preventing glutamate-mediated excitotoxicity. Crystallographic studies on an archaeal homologue, Glt(Ph), showed that distinct transp...
Uloženo v:
| Vydáno v: | Nature |
|---|---|
| Hlavní autoři: | , , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4351760/ https://ncbi.nlm.nih.gov/pubmed/25652997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14158 |
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