FAAH genetic variation enhances fronto-amygdala function in mouse and human

Cross-species studies enable rapid translational discovery and produce the broadest impact when both mechanism and phenotype are consistent across organisms. We developed a knock-in mouse that biologically recapitulates a common human mutation in the gene for fatty acid amide hydrolase (FAAH) (C385A...

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Publié dans:Nat Commun
Auteurs principaux: Dincheva, Iva, Drysdale, Andrew T., Hartley, Catherine A., Johnson, David C., Jing, Deqiang, King, Elizabeth C., Ra, Stephen, Gray, Megan, Yang, Ruirong, DeGruccio, Ann Marie, Huang, Chienchun, Cravatt, Benjamin F., Glatt, Charles E., Hill, Matthew N., Casey, B. J., Lee, Francis S.
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351757/
https://ncbi.nlm.nih.gov/pubmed/25731744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7395
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