FAAH genetic variation enhances fronto-amygdala function in mouse and human

Cross-species studies enable rapid translational discovery and produce the broadest impact when both mechanism and phenotype are consistent across organisms. We developed a knock-in mouse that biologically recapitulates a common human mutation in the gene for fatty acid amide hydrolase (FAAH) (C385A...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Dincheva, Iva, Drysdale, Andrew T., Hartley, Catherine A., Johnson, David C., Jing, Deqiang, King, Elizabeth C., Ra, Stephen, Gray, Megan, Yang, Ruirong, DeGruccio, Ann Marie, Huang, Chienchun, Cravatt, Benjamin F., Glatt, Charles E., Hill, Matthew N., Casey, B. J., Lee, Francis S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351757/
https://ncbi.nlm.nih.gov/pubmed/25731744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7395
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