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Essential role of maternal UCHL1 and UCHL3 in fertilization and preimplantation embryo development

Posttranslational protein modification by ubiquitination, a signal for lysosomal or proteasomal proteolysis, can be regulated and reversed by deubiquitinating enzymes (DUBs). This study examined the roles of UCHL1 and UCHL3, two members of ubiquitin C-terminal hydrolase (UCH) family of DUBs, in muri...

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Detalhes bibliográficos
Publicado no:J Cell Physiol
Main Authors: Mtango, Namdori R., Sutovsky, Miriam, Susor, Andrej, Zhong, Zhisheng, Latham, Keith E., Sutovsky, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351554/
https://ncbi.nlm.nih.gov/pubmed/21678411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.22876
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