Amphiregulin activates human hepatic stellate cells and is upregulated in non alcoholic steatohepatitis

Amphiregulin (AR) involvement in liver fibrogenesis and hepatic stellate cells (HSC) regulation is under study. Non-alcoholic fatty liver disease (NAFLD) and its more severe form non-alcoholic steatohepatitis (NASH) may progress to cirrhosis and hepatocellular cancer (HCC). Our aim was to investigat...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: McKee, Chad, Sigala, Barbara, Soeda, Junpei, Mouralidarane, Angelina, Morgan, Maelle, Mazzoccoli, Gianluigi, Rappa, Francesca, Cappello, Francesco, Cabibi, Daniela, Pazienza, Valerio, Selden, Claire, Roskams, Tania, Vinciguerra, Manlio, Oben, Jude A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351520/
https://ncbi.nlm.nih.gov/pubmed/25744849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08812
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