Dietary Methionine Restriction in Mice Elicits an Adaptive Cardiovascular Response to Hyperhomocysteinemia

Dietary methionine restriction (MR) in rodents increased lifespan despite higher heart-to-body weight ratio (w/w) and hyperhomocysteinemia, which are symptoms associated with increased risk for cardiovascular disease. We investigated this paradoxical effect of MR on cardiac function using young, old...

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Udgivet i:Sci Rep
Main Authors: Ables, Gene P., Ouattara, Amadou, Hampton, Thomas G., Cooke, Diana, Perodin, Frantz, Augie, Ines, Orentreich, David S.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351514/
https://ncbi.nlm.nih.gov/pubmed/25744495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08886
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