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Optogenetic release of norepinephrine from cardiac sympathetic neurons alters mechanical and electrical function

AIMS: Release of norepinephrine (NE) from sympathetic neurons enhances heart rate (HR) and developed force through activation of β-adrenergic receptors, and this sympathoexcitation is a key risk for the generation of cardiac arrhythmias. Studies of β-adrenergic modulation of cardiac function typical...

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Detalhes bibliográficos
Publicado no:Cardiovasc Res
Main Authors: Wengrowski, Anastasia M., Wang, Xin, Tapa, Srinivas, Posnack, Nikki Gillum, Mendelowitz, David, Kay, Matthew W.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351353/
https://ncbi.nlm.nih.gov/pubmed/25514932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvu258
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