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Dysregulation of X Chromosome Inactivation in High Grade Ovarian Serous Adenocarcinoma
BACKGROUND: One of the two copies of the X chromosome is randomly inactivated in females as a means of dosage compensation. Loss of X chromosome inactivation (XCI) is observed in breast and ovarian cancers, and is frequent in basal-like subtype and BRCA1 mutation-associated breast cancers. We invest...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4351149/ https://ncbi.nlm.nih.gov/pubmed/25742136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118927 |
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