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Spindle Assembly Checkpoint Acquisition at the Mid-Blastula Transition

The spindle assembly checkpoint (SAC) maintains the fidelity of chromosome segregation during mitosis. Nonpathogenic cells lacking the SAC are typically only found in cleavage stage metazoan embryos, which do not acquire functional checkpoints until the mid-blastula transition (MBT). It is unclear h...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zhang, Maomao, Kothari, Priyanka, Lampson, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351100/
https://ncbi.nlm.nih.gov/pubmed/25741707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119285
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