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Linear combinations of biomarkers to improve diagnostic accuracy with three ordinal diagnostic categories

Many researchers have addressed the problem of finding the optimal linear combination of biomarkers to maximize the area under receiver operating characteristic (ROC) curves for scenarios with binary disease status. In practice, many disease processes such as Alzheimer can be naturally classified in...

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Bibliographic Details
Published in:Stat Med
Main Authors: Kang, Le, Xiong, Chengjie, Crane, Paul, Tian, Lili
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351049/
https://ncbi.nlm.nih.gov/pubmed/22865796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.5542
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